Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse

The most frequent ocular manifestation of acquired immunodeficiency syndrome (AIDS) is cytomegalovirus retinitis (CMVR). This infection is reportedly inversely proportional to the CD4 counts. Usually CMVR develops once the CD4 counts fall below 50/mm(3). Our case report documents an AIDS patient who...

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Autores principales: Keat, Gan Yuen, Ahmad, Syed Shoeb, Subramaniam, Suresh, Ghani, Shuaibah Abdul, Samsudin, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529169/
https://www.ncbi.nlm.nih.gov/pubmed/33062999
http://dx.doi.org/10.4103/ijstd.IJSTD_90_15
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author Keat, Gan Yuen
Ahmad, Syed Shoeb
Subramaniam, Suresh
Ghani, Shuaibah Abdul
Samsudin, Amir
author_facet Keat, Gan Yuen
Ahmad, Syed Shoeb
Subramaniam, Suresh
Ghani, Shuaibah Abdul
Samsudin, Amir
author_sort Keat, Gan Yuen
collection PubMed
description The most frequent ocular manifestation of acquired immunodeficiency syndrome (AIDS) is cytomegalovirus retinitis (CMVR). This infection is reportedly inversely proportional to the CD4 counts. Usually CMVR develops once the CD4 counts fall below 50/mm(3). Our case report documents an AIDS patient who developed CMVR despite CD4 counts being persistently >200/mm(3). The patient was self-administering dehydroepiandrosterone, high dose Vitamin C, testosterone and hydrocortisone. This case report describes a unique case of pharmacologically induced elevated CD4 counts, which however, did not prevent the development of CMVR in the patient.
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spelling pubmed-75291692020-10-13 Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse Keat, Gan Yuen Ahmad, Syed Shoeb Subramaniam, Suresh Ghani, Shuaibah Abdul Samsudin, Amir Indian J Sex Transm Dis AIDS Case Reports The most frequent ocular manifestation of acquired immunodeficiency syndrome (AIDS) is cytomegalovirus retinitis (CMVR). This infection is reportedly inversely proportional to the CD4 counts. Usually CMVR develops once the CD4 counts fall below 50/mm(3). Our case report documents an AIDS patient who developed CMVR despite CD4 counts being persistently >200/mm(3). The patient was self-administering dehydroepiandrosterone, high dose Vitamin C, testosterone and hydrocortisone. This case report describes a unique case of pharmacologically induced elevated CD4 counts, which however, did not prevent the development of CMVR in the patient. Wolters Kluwer - Medknow 2020 2020-06-18 /pmc/articles/PMC7529169/ /pubmed/33062999 http://dx.doi.org/10.4103/ijstd.IJSTD_90_15 Text en Copyright: © 2020 Indian Journal of Sexually Transmitted Diseases and AIDS http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Keat, Gan Yuen
Ahmad, Syed Shoeb
Subramaniam, Suresh
Ghani, Shuaibah Abdul
Samsudin, Amir
Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse
title Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse
title_full Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse
title_fullStr Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse
title_full_unstemmed Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse
title_short Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse
title_sort cytomegalovirus retinitis associated with high cd4 counts and dhea abuse
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529169/
https://www.ncbi.nlm.nih.gov/pubmed/33062999
http://dx.doi.org/10.4103/ijstd.IJSTD_90_15
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