Luteolin-mediated Kv1.3 K(+) channel inhibition augments BCG vaccine efficacy against tuberculosis by promoting central memory T cell responses in mice

Despite the availability of multiple antibiotics, tuberculosis (TB) remains a major health problem worldwide, with one third of the population latently infected and ~2 million deaths annually. The only available vaccine for TB, Bacillus Calmette Guérin (BCG), is ineffective against adult pulmonary T...

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Detalles Bibliográficos
Autores principales: Singh, Dhiraj Kumar, Dwivedi, Ved Prakash, Singh, Shashi Prakash, Kumari, Anjna, Sharma, Saurabh Kumar, Ranganathan, Anand, Kaer, Luc Van, Das, Gobardhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529197/
https://www.ncbi.nlm.nih.gov/pubmed/32956412
http://dx.doi.org/10.1371/journal.ppat.1008887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529197/
https://www.ncbi.nlm.nih.gov/pubmed/32956412
http://dx.doi.org/10.1371/journal.ppat.1008887

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