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Luteolin-mediated Kv1.3 K(+) channel inhibition augments BCG vaccine efficacy against tuberculosis by promoting central memory T cell responses in mice
Despite the availability of multiple antibiotics, tuberculosis (TB) remains a major health problem worldwide, with one third of the population latently infected and ~2 million deaths annually. The only available vaccine for TB, Bacillus Calmette Guérin (BCG), is ineffective against adult pulmonary T...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529197/ https://www.ncbi.nlm.nih.gov/pubmed/32956412 http://dx.doi.org/10.1371/journal.ppat.1008887 |