Physical activity prevents acute inflammation in a gout model by downregulation of TLR2 on circulating neutrophils as well as inhibition of serum CXCL1 and is associated with decreased pain and inflammation in gout patients

OBJECTIVES: Gout is the most prevalent inflammatory arthritis. To study the effects of regular physical activity and exercise intensity on inflammation and clinical outcome, we examined inflammatory pathogenesis in an acute model of murine gout and analyzed human gout patient clinical data as a func...

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Detalles Bibliográficos
Autores principales: Jablonski, Kyle, Young, Nicholas A., Henry, Caitlin, Caution, Kyle, Kalyanasundaram, Anuradha, Okafor, Ifeoma, Harb, Peter, Schwarz, Emmy, Consiglio, Paul, Cirimotich, Chris M., Bratasz, Anna, Sarkar, Anasuya, Amer, Amal O., Jarjour, Wael N., Schlesinger, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529261/
https://www.ncbi.nlm.nih.gov/pubmed/33002030
http://dx.doi.org/10.1371/journal.pone.0237520

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