Zika virus-based immunotherapy enhances long-term survival of rodents with brain tumors through upregulation of memory T-cells

Zika virus (ZIKV) exhibits a tropism for brain tumor cells and has been used as an oncolytic virus to target brain tumors in mice with modest effects on extending median survival. Recent studies have highlighted the potential for combining virotherapy and immunotherapy to target cancer. We postulate...

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Detalles Bibliográficos
Autores principales: Crane, Andrew T., Chrostek, Matthew R., Krishna, Venkatramana D., Shiao, Maple, Toman, Nikolas G., Pearce, Clairice M., Tran, Sarah K., Sipe, Christopher J., Guo, Winston, Voth, Joseph P., Vaid, Shivanshi, Xie, Hui, Lu, Wei-Cheng, Swanson, Will, Grande, Andrew W., Schleiss, Mark R., Bierle, Craig J., Cheeran, Maxim C-J., Low, Walter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529292/
https://www.ncbi.nlm.nih.gov/pubmed/33002018
http://dx.doi.org/10.1371/journal.pone.0232858

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