Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci

Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants and genes underlying these associations remain undetermined. Identifying these...

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Detalles Bibliográficos
Autores principales: Gaare, Johannes Jernqvist, Nido, Gonzalo, Dölle, Christian, Sztromwasser, Paweł, Alves, Guido, Tysnes, Ole-Bjørn, Haugarvoll, Kristoffer, Tzoulis, Charalampos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529297/
https://www.ncbi.nlm.nih.gov/pubmed/33002040
http://dx.doi.org/10.1371/journal.pone.0239824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529297/
https://www.ncbi.nlm.nih.gov/pubmed/33002040
http://dx.doi.org/10.1371/journal.pone.0239824

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