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Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes

Few studies provide an analysis of conservative two-stage revision of hip periprosthetic joint infection (PJI) and its impact on final outcome. A conservative revision is defined when soft tissues and bone quality enable the use of primary prosthetic components. Data of patients treated for chronic...

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Autores principales: Burastero, Giorgio, Alessio-Mazzola, Mattia, Cavagnaro, Luca, Chiarlone, Francesco, Carrega, Giuliana, Capello, Andrea Giorgio, Lovisolo, Stefano, Felli, Lamberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529346/
https://www.ncbi.nlm.nih.gov/pubmed/33002069
http://dx.doi.org/10.1371/journal.pone.0239981
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author Burastero, Giorgio
Alessio-Mazzola, Mattia
Cavagnaro, Luca
Chiarlone, Francesco
Carrega, Giuliana
Capello, Andrea Giorgio
Lovisolo, Stefano
Felli, Lamberto
author_facet Burastero, Giorgio
Alessio-Mazzola, Mattia
Cavagnaro, Luca
Chiarlone, Francesco
Carrega, Giuliana
Capello, Andrea Giorgio
Lovisolo, Stefano
Felli, Lamberto
author_sort Burastero, Giorgio
collection PubMed
description Few studies provide an analysis of conservative two-stage revision of hip periprosthetic joint infection (PJI) and its impact on final outcome. A conservative revision is defined when soft tissues and bone quality enable the use of primary prosthetic components. Data of patients treated for chronic hip PJI who underwent two-stage revision between 2009 and 2016 and had a minimum of 2 years of follow-up were collected. Oxford Hip Score (OHS), Harris Hip Score (HHS) and radiological and microbiological data were retrieved and analysed. Clinical and functional outcome, survival, mortality, eradication, reinfection and re-revision rates within subgroups of patients with primary components and revision components are reported herein. A total of 148 patients underwent two-stage hip exchange with a mean follow-up of 55.6 ± 23.1 months and a mean age at surgery of 64.3 ± 12.7 years. Forty-four percent of patients underwent conservative revision. The mean HHS significantly improved from 40.6 ± 9.4 points to the final value of 87.8 ± 10.5 points (p = .002), and the mean OHS went from 20.3 ± 3.8 points to 40.3 ± 5. points (p< .001). Patients who were treated with primary components or isolated revision stems in the second stage had a significant reduction in surgical times (p< .001). The mortality rate for all causes of death was 6.8%, the eradication rate was 89.9%, the reinfection rate was 4.7% and the reoperation rate was 7.4% without differences between conservative and non-conservative revisions. Two-stage exchange arthroplasty for total hip arthroplasty (THA) PJI is a good strategy that provides satisfactory results, high eradication rates and no further need for revision. The conservative two-stage revision in patients with adequate bone stock represents a feasible option with good results and survival rates.
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spelling pubmed-75293462020-10-08 Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes Burastero, Giorgio Alessio-Mazzola, Mattia Cavagnaro, Luca Chiarlone, Francesco Carrega, Giuliana Capello, Andrea Giorgio Lovisolo, Stefano Felli, Lamberto PLoS One Research Article Few studies provide an analysis of conservative two-stage revision of hip periprosthetic joint infection (PJI) and its impact on final outcome. A conservative revision is defined when soft tissues and bone quality enable the use of primary prosthetic components. Data of patients treated for chronic hip PJI who underwent two-stage revision between 2009 and 2016 and had a minimum of 2 years of follow-up were collected. Oxford Hip Score (OHS), Harris Hip Score (HHS) and radiological and microbiological data were retrieved and analysed. Clinical and functional outcome, survival, mortality, eradication, reinfection and re-revision rates within subgroups of patients with primary components and revision components are reported herein. A total of 148 patients underwent two-stage hip exchange with a mean follow-up of 55.6 ± 23.1 months and a mean age at surgery of 64.3 ± 12.7 years. Forty-four percent of patients underwent conservative revision. The mean HHS significantly improved from 40.6 ± 9.4 points to the final value of 87.8 ± 10.5 points (p = .002), and the mean OHS went from 20.3 ± 3.8 points to 40.3 ± 5. points (p< .001). Patients who were treated with primary components or isolated revision stems in the second stage had a significant reduction in surgical times (p< .001). The mortality rate for all causes of death was 6.8%, the eradication rate was 89.9%, the reinfection rate was 4.7% and the reoperation rate was 7.4% without differences between conservative and non-conservative revisions. Two-stage exchange arthroplasty for total hip arthroplasty (THA) PJI is a good strategy that provides satisfactory results, high eradication rates and no further need for revision. The conservative two-stage revision in patients with adequate bone stock represents a feasible option with good results and survival rates. Public Library of Science 2020-10-01 /pmc/articles/PMC7529346/ /pubmed/33002069 http://dx.doi.org/10.1371/journal.pone.0239981 Text en © 2020 Burastero et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Burastero, Giorgio
Alessio-Mazzola, Mattia
Cavagnaro, Luca
Chiarlone, Francesco
Carrega, Giuliana
Capello, Andrea Giorgio
Lovisolo, Stefano
Felli, Lamberto
Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes
title Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes
title_full Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes
title_fullStr Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes
title_full_unstemmed Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes
title_short Conservative two-stage revision with primary components of infected total hip arthroplasty: An analysis of survival, clinical and radiographic outcomes
title_sort conservative two-stage revision with primary components of infected total hip arthroplasty: an analysis of survival, clinical and radiographic outcomes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529346/
https://www.ncbi.nlm.nih.gov/pubmed/33002069
http://dx.doi.org/10.1371/journal.pone.0239981
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