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REV-ERB agonism improves liver pathology in a mouse model of NASH

Non-alcoholic fatty liver disease (NAFLD) affects a significant number of people worldwide and currently there are no pharmacological treatments. NAFLD often presents with obesity, insulin resistance, and in some cases cardiovascular diseases. There is a clear need for treatment options to alleviate...

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Detalles Bibliográficos
Autores principales: Griffett, Kristine, Bedia-Diaz, Gonzalo, Elgendy, Bahaa, Burris, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529425/
https://www.ncbi.nlm.nih.gov/pubmed/33002003
http://dx.doi.org/10.1371/journal.pone.0236000