Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth

The umbilical artery lumen closes rapidly at birth, preventing neonatal blood loss, whereas the umbilical vein remains patent longer. Here, analysis of umbilical cords from humans and other mammals identified differential arterial-venous proteoglycan dynamics as a determinant of these contrasting va...

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Detalles Bibliográficos
Autores principales: Nandadasa, Sumeda, Szafron, Jason M, Pathak, Vai, Murtada, Sae-Il, Kraft, Caroline M, O'Donnell, Anna, Norvik, Christian, Hughes, Clare, Caterson, Bruce, Domowicz, Miriam S, Schwartz, Nancy B, Tran-Lundmark, Karin, Veigl, Martina, Sedwick, David, Philipson, Elliot H, Humphrey, Jay D, Apte, Suneel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529456/
https://www.ncbi.nlm.nih.gov/pubmed/32909945
http://dx.doi.org/10.7554/eLife.60683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529456/
https://www.ncbi.nlm.nih.gov/pubmed/32909945
http://dx.doi.org/10.7554/eLife.60683

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