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Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke out in Wuhan, China, and subsequently spread worldwide affecting all ages including newborns. The cases of coronavirus disease 2019 (COVID-19) are very less in neonates and they recover well with supportive treatment. Thoug...

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Autores principales: Nayak, Manas, Panda, Santosh, Pradhan, Janaki Ballav, Mohakud, Nirmal K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529492/
https://www.ncbi.nlm.nih.gov/pubmed/33029451
http://dx.doi.org/10.7759/cureus.10171
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author Nayak, Manas
Panda, Santosh
Pradhan, Janaki Ballav
Mohakud, Nirmal K
author_facet Nayak, Manas
Panda, Santosh
Pradhan, Janaki Ballav
Mohakud, Nirmal K
author_sort Nayak, Manas
collection PubMed
description The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke out in Wuhan, China, and subsequently spread worldwide affecting all ages including newborns. The cases of coronavirus disease 2019 (COVID-19) are very less in neonates and they recover well with supportive treatment. Though the vertical transmission of infection is scarcely found, to get rid of acquiring infection by horizontal transmission one should screen all pregnant women and ensure standard infection control measures and monitoring of newborns at risk of COVID-19. Neonates may present as a refusal to feed, feeding intolerance, fever, pneumonia, shortness of breath, and lethargic. Based on available evidence, antivirals like lopinavir, ritonavir, remdesivir specific medication like chloroquine/hydroxychloroquine, azithromycin, corticosteroids, and intravenous gamma globulin, are not recommended, so early detection and supportive treatment is needed for an optimal outcome.
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spelling pubmed-75294922020-10-06 Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known Nayak, Manas Panda, Santosh Pradhan, Janaki Ballav Mohakud, Nirmal K Cureus Pediatrics The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke out in Wuhan, China, and subsequently spread worldwide affecting all ages including newborns. The cases of coronavirus disease 2019 (COVID-19) are very less in neonates and they recover well with supportive treatment. Though the vertical transmission of infection is scarcely found, to get rid of acquiring infection by horizontal transmission one should screen all pregnant women and ensure standard infection control measures and monitoring of newborns at risk of COVID-19. Neonates may present as a refusal to feed, feeding intolerance, fever, pneumonia, shortness of breath, and lethargic. Based on available evidence, antivirals like lopinavir, ritonavir, remdesivir specific medication like chloroquine/hydroxychloroquine, azithromycin, corticosteroids, and intravenous gamma globulin, are not recommended, so early detection and supportive treatment is needed for an optimal outcome. Cureus 2020-08-31 /pmc/articles/PMC7529492/ /pubmed/33029451 http://dx.doi.org/10.7759/cureus.10171 Text en Copyright © 2020, Nayak et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Nayak, Manas
Panda, Santosh
Pradhan, Janaki Ballav
Mohakud, Nirmal K
Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known
title Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known
title_full Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known
title_fullStr Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known
title_full_unstemmed Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known
title_short Coronavirus Disease 2019 in Neonates – What Is Known and What Needs to Be Known
title_sort coronavirus disease 2019 in neonates – what is known and what needs to be known
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529492/
https://www.ncbi.nlm.nih.gov/pubmed/33029451
http://dx.doi.org/10.7759/cureus.10171
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