EGF+61 A>G polymorphism does not predict response to first‐generation EGFR tyrosine kinase inhibitors in lung cancer patients

Epidermal growth factor (EGF) and its receptor (EGFR) play a paramount role in lung carcinogenesis. The polymorphism in the EGF promoter region EGF+61A>G (rs4444903) has been associated with cancer susceptibility, but its role in lung cancer patients treated with tyrosine kinase inhibitors (TKIs)...

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Detalles Bibliográficos
Autores principales: Leal, Leticia F., Laus, Ana C., Cavagna, Rodrigo, de Paula, Flavia E., de Oliveira, Marco A., Ribeiro, Dayana M., Hassan, Fernanda M., Miziara, José E., da Silva, Eduardo C. Albino, da Silva, Vinicius D., De Marchi, Pedro, Reis, Rui M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529554/
https://www.ncbi.nlm.nih.gov/pubmed/32881389
http://dx.doi.org/10.1111/1759-7714.13628

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