Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19

We describe a patient with coronavirus disease 2019 (COVID-19) and multiple concomitant thromboses occurring on the 9th day of hospital stay. Thromboses were found in distinct zones of the aorta, as well as in the renal, humeral, and pulmonary arteries. The extensive biological workup performed foll...

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Detalles Bibliográficos
Autores principales: Kenizou, David, Perrin, Clemence, Harzallah, Ines, Bresson, Didier, Allimant, Patrick, Calcaianu, Mihaela, Lawson, Bree, Morisset, Béatrice, Zuily, Stephane, Jacquemin, Laurent, Kinnel, Marine, Girerd, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529607/
https://www.ncbi.nlm.nih.gov/pubmed/33024951
http://dx.doi.org/10.1016/j.cjco.2020.09.020
Descripción
Sumario:We describe a patient with coronavirus disease 2019 (COVID-19) and multiple concomitant thromboses occurring on the 9th day of hospital stay. Thromboses were found in distinct zones of the aorta, as well as in the renal, humeral, and pulmonary arteries. The extensive biological workup performed following this catastrophic thrombotic syndrome found no evidence for underlying prothrombotic disease. In light of current evidence regarding endothelium abnormalities related to COVID-19, this extreme case of catastrophic thrombotic syndrome suggests that COVID-19 can induce severe arterial thrombosis following intense endothelial activation.

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