Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19

We describe a patient with coronavirus disease 2019 (COVID-19) and multiple concomitant thromboses occurring on the 9th day of hospital stay. Thromboses were found in distinct zones of the aorta, as well as in the renal, humeral, and pulmonary arteries. The extensive biological workup performed foll...

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Autores principales: Kenizou, David, Perrin, Clemence, Harzallah, Ines, Bresson, Didier, Allimant, Patrick, Calcaianu, Mihaela, Lawson, Bree, Morisset, Béatrice, Zuily, Stephane, Jacquemin, Laurent, Kinnel, Marine, Girerd, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529607/
https://www.ncbi.nlm.nih.gov/pubmed/33024951
http://dx.doi.org/10.1016/j.cjco.2020.09.020
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author Kenizou, David
Perrin, Clemence
Harzallah, Ines
Bresson, Didier
Allimant, Patrick
Calcaianu, Mihaela
Lawson, Bree
Morisset, Béatrice
Zuily, Stephane
Jacquemin, Laurent
Kinnel, Marine
Girerd, Nicolas
author_facet Kenizou, David
Perrin, Clemence
Harzallah, Ines
Bresson, Didier
Allimant, Patrick
Calcaianu, Mihaela
Lawson, Bree
Morisset, Béatrice
Zuily, Stephane
Jacquemin, Laurent
Kinnel, Marine
Girerd, Nicolas
author_sort Kenizou, David
collection PubMed
description We describe a patient with coronavirus disease 2019 (COVID-19) and multiple concomitant thromboses occurring on the 9th day of hospital stay. Thromboses were found in distinct zones of the aorta, as well as in the renal, humeral, and pulmonary arteries. The extensive biological workup performed following this catastrophic thrombotic syndrome found no evidence for underlying prothrombotic disease. In light of current evidence regarding endothelium abnormalities related to COVID-19, this extreme case of catastrophic thrombotic syndrome suggests that COVID-19 can induce severe arterial thrombosis following intense endothelial activation.
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spelling pubmed-75296072020-10-02 Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19 Kenizou, David Perrin, Clemence Harzallah, Ines Bresson, Didier Allimant, Patrick Calcaianu, Mihaela Lawson, Bree Morisset, Béatrice Zuily, Stephane Jacquemin, Laurent Kinnel, Marine Girerd, Nicolas CJC Open Case Report We describe a patient with coronavirus disease 2019 (COVID-19) and multiple concomitant thromboses occurring on the 9th day of hospital stay. Thromboses were found in distinct zones of the aorta, as well as in the renal, humeral, and pulmonary arteries. The extensive biological workup performed following this catastrophic thrombotic syndrome found no evidence for underlying prothrombotic disease. In light of current evidence regarding endothelium abnormalities related to COVID-19, this extreme case of catastrophic thrombotic syndrome suggests that COVID-19 can induce severe arterial thrombosis following intense endothelial activation. Elsevier 2020-10-02 /pmc/articles/PMC7529607/ /pubmed/33024951 http://dx.doi.org/10.1016/j.cjco.2020.09.020 Text en © 2020 Canadian Cardiovascular Society. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kenizou, David
Perrin, Clemence
Harzallah, Ines
Bresson, Didier
Allimant, Patrick
Calcaianu, Mihaela
Lawson, Bree
Morisset, Béatrice
Zuily, Stephane
Jacquemin, Laurent
Kinnel, Marine
Girerd, Nicolas
Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19
title Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19
title_full Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19
title_fullStr Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19
title_full_unstemmed Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19
title_short Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19
title_sort multiple arterial thrombosis in a 78-year-old patient: catastrophic thrombotic syndrome in covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529607/
https://www.ncbi.nlm.nih.gov/pubmed/33024951
http://dx.doi.org/10.1016/j.cjco.2020.09.020
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