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Predicting pattern formation in embryonic stem cells using a minimalist, agent-based probabilistic model

The mechanisms of pattern formation during embryonic development remain poorly understood. Embryonic stem cells in culture self-organise to form spatial patterns of gene expression upon geometrical confinement indicating that patterning is an emergent phenomenon that results from the many interactio...

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Detalles Bibliográficos
Autores principales: Wang, Minhong, Tsanas, Athanasios, Blin, Guillaume, Robertson, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529768/
https://www.ncbi.nlm.nih.gov/pubmed/33004880
http://dx.doi.org/10.1038/s41598-020-73228-4