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Predicting pattern formation in embryonic stem cells using a minimalist, agent-based probabilistic model
The mechanisms of pattern formation during embryonic development remain poorly understood. Embryonic stem cells in culture self-organise to form spatial patterns of gene expression upon geometrical confinement indicating that patterning is an emergent phenomenon that results from the many interactio...
Autores principales: | Wang, Minhong, Tsanas, Athanasios, Blin, Guillaume, Robertson, Dave |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529768/ https://www.ncbi.nlm.nih.gov/pubmed/33004880 http://dx.doi.org/10.1038/s41598-020-73228-4 |
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