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Identification of putative master regulators in rheumatoid arthritis synovial fibroblasts using gene expression data and network inference

Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects the synovial joints of the body. Rheumatoid arthritis fibroblast-like synoviocytes (RA FLS) are central players in the disease pathogenesis, as they are involved in the secretion of cytokines and proteolytic enzymes, exhibit inv...

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Detalles Bibliográficos
Autores principales: Zerrouk, Naouel, Miagoux, Quentin, Dispot, Aurelien, Elati, Mohamed, Niarakis, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529794/
https://www.ncbi.nlm.nih.gov/pubmed/33004899
http://dx.doi.org/10.1038/s41598-020-73147-4