Cargando…
Identification of putative master regulators in rheumatoid arthritis synovial fibroblasts using gene expression data and network inference
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects the synovial joints of the body. Rheumatoid arthritis fibroblast-like synoviocytes (RA FLS) are central players in the disease pathogenesis, as they are involved in the secretion of cytokines and proteolytic enzymes, exhibit inv...
Autores principales: | Zerrouk, Naouel, Miagoux, Quentin, Dispot, Aurelien, Elati, Mohamed, Niarakis, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529794/ https://www.ncbi.nlm.nih.gov/pubmed/33004899 http://dx.doi.org/10.1038/s41598-020-73147-4 |
Ejemplares similares
-
Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer: Deciphering Key Mechanisms Using Computational Systems Biology Approaches
por: Aghakhani, Sahar, et al.
Publicado: (2020) -
Inference of an Integrative, Executable Network for Rheumatoid Arthritis Combining Data-Driven Machine Learning Approaches and a State-of-the-Art Mechanistic Disease Map
por: Miagoux, Quentin, et al.
Publicado: (2021) -
Metabolic reprogramming in Rheumatoid Arthritis Synovial Fibroblasts: A hybrid modeling approach
por: Aghakhani, Sahar, et al.
Publicado: (2022) -
Latent network-based representations for large-scale gene expression data analysis
por: Dhifli, Wajdi, et al.
Publicado: (2019) -
Activation of Synovial Fibroblasts in Rheumatoid Arthritis
por: Gay, Steffen, et al.
Publicado: (2000)