Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing

Viruses promote infection by hijacking host ubiquitin machinery to counteract or redirect cellular processes. Adenovirus encodes two early proteins, E1B55K and E4orf6, that together co-opt a cellular ubiquitin ligase complex to overcome host defenses and promote virus production. Adenovirus mutants...

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Detalles Bibliográficos
Autores principales: Herrmann, Christin, Dybas, Joseph M., Liddle, Jennifer C., Price, Alexander M, Hayer, Katharina E., Lauman, Richard, Purman, Caitlin E., Charman, Matthew, Kim, Eui Tae, Garcia, Benjamin A, Weitzman, Matthew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529849/
https://www.ncbi.nlm.nih.gov/pubmed/32661314
http://dx.doi.org/10.1038/s41564-020-0750-9

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