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Microbiota-derived metabolite promotes HDAC3 activity in the gut
The coevolution of mammalian hosts and their beneficial commensal microbes has led to development of a symbiotic host-microbiota relationship(1). Epigenetic machinery permits mammalian cells to integrate environmental signals(2), however, how these pathways are finely tuned by diverse cues from comm...
Autores principales: | Wu, Shu-en, Hashimoto-Hill, Seika, Woo, Vivienne, Eshleman, Emily M., Whitt, Jordan, Engleman, Laura, Karns, Rebekah, Denson, Lee A., Haslam, David B., Alenghat, Theresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529926/ https://www.ncbi.nlm.nih.gov/pubmed/32731255 http://dx.doi.org/10.1038/s41586-020-2604-2 |
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