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N-Glycosylation of monoclonal light chains on routine MASS-FIX testing is a risk factor for MGUS progression

Our group previously demonstrated that M-protein light chain (LC) glycosylation can be detected on routine MASS-FIX testing. Glycosylation is increased in patients with immunoglobulin light chain amyloidosis (AL) and rarely changes over the course of a patient’s lifetime. To determine the rates of p...

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Detalles Bibliográficos
Autores principales: Dispenzieri, Angela, Larson, D.R., Rajkumar, S.V., Kyle, R.A., Kumar, S.K., Kourelis, Taxiarchis, Arendt, Bonnie, Willrcih, Maria, Dasari, Surendra, Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529948/
https://www.ncbi.nlm.nih.gov/pubmed/32594098
http://dx.doi.org/10.1038/s41375-020-0940-8