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Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals

Recent statistics have shown that the main difficulty in detecting alcoholism is the unreliability of the information presented by patients with alcoholism; this factor confusing the early diagnosis and it can reduce the effectiveness of treatment. However, electroencephalogram (EEG) exams can provi...

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Autores principales: Zhang, Hongyi, Silva, Francisco H. S., Ohata, Elene F., Medeiros, Aldisio G., Rebouças Filho, Pedro P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530264/
https://www.ncbi.nlm.nih.gov/pubmed/33061900
http://dx.doi.org/10.3389/fnhum.2020.00365
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author Zhang, Hongyi
Silva, Francisco H. S.
Ohata, Elene F.
Medeiros, Aldisio G.
Rebouças Filho, Pedro P.
author_facet Zhang, Hongyi
Silva, Francisco H. S.
Ohata, Elene F.
Medeiros, Aldisio G.
Rebouças Filho, Pedro P.
author_sort Zhang, Hongyi
collection PubMed
description Recent statistics have shown that the main difficulty in detecting alcoholism is the unreliability of the information presented by patients with alcoholism; this factor confusing the early diagnosis and it can reduce the effectiveness of treatment. However, electroencephalogram (EEG) exams can provide more reliable data for analysis of this behavior. This paper proposes a new approach for the automatic diagnosis of patients with alcoholism and introduces an analysis of the EEG signals from a two-dimensional perspective according to changes in the neural activity, highlighting the influence of high and low-frequency signals. This approach uses a two-dimensional feature extraction method, as well as the application of recent Computer Vision (CV) techniques, such as Transfer Learning with Convolutional Neural Networks (CNN). The methodology to evaluate our proposal used 21 combinations of the traditional classification methods and 84 combinations of recent CNN architectures used as feature extractors combined with the following classical classifiers: Gaussian Naive Bayes, K-Nearest Neighbor (k-NN), Multilayer Perceptron (MLP), Random Forest (RF) and Support Vector Machine (SVM). CNN MobileNet combined with SVM achieved the best results in Accuracy (95.33%), Precision (95.68%), F1-Score (95.24%), and Recall (95.00%). This combination outperformed the traditional methods by up to 8%. Thus, this approach is applicable as a classification stage for computer-aided diagnoses, useful for the triage of patients, and clinical support for the early diagnosis of this disease.
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spelling pubmed-75302642020-10-13 Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals Zhang, Hongyi Silva, Francisco H. S. Ohata, Elene F. Medeiros, Aldisio G. Rebouças Filho, Pedro P. Front Hum Neurosci Human Neuroscience Recent statistics have shown that the main difficulty in detecting alcoholism is the unreliability of the information presented by patients with alcoholism; this factor confusing the early diagnosis and it can reduce the effectiveness of treatment. However, electroencephalogram (EEG) exams can provide more reliable data for analysis of this behavior. This paper proposes a new approach for the automatic diagnosis of patients with alcoholism and introduces an analysis of the EEG signals from a two-dimensional perspective according to changes in the neural activity, highlighting the influence of high and low-frequency signals. This approach uses a two-dimensional feature extraction method, as well as the application of recent Computer Vision (CV) techniques, such as Transfer Learning with Convolutional Neural Networks (CNN). The methodology to evaluate our proposal used 21 combinations of the traditional classification methods and 84 combinations of recent CNN architectures used as feature extractors combined with the following classical classifiers: Gaussian Naive Bayes, K-Nearest Neighbor (k-NN), Multilayer Perceptron (MLP), Random Forest (RF) and Support Vector Machine (SVM). CNN MobileNet combined with SVM achieved the best results in Accuracy (95.33%), Precision (95.68%), F1-Score (95.24%), and Recall (95.00%). This combination outperformed the traditional methods by up to 8%. Thus, this approach is applicable as a classification stage for computer-aided diagnoses, useful for the triage of patients, and clinical support for the early diagnosis of this disease. Frontiers Media S.A. 2020-09-18 /pmc/articles/PMC7530264/ /pubmed/33061900 http://dx.doi.org/10.3389/fnhum.2020.00365 Text en Copyright © 2020 Zhang, Silva, Ohata, Medeiros and Rebouças Filho. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Human Neuroscience
Zhang, Hongyi
Silva, Francisco H. S.
Ohata, Elene F.
Medeiros, Aldisio G.
Rebouças Filho, Pedro P.
Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals
title Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals
title_full Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals
title_fullStr Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals
title_full_unstemmed Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals
title_short Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals
title_sort bi-dimensional approach based on transfer learning for alcoholism pre-disposition classification via eeg signals
topic Human Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530264/
https://www.ncbi.nlm.nih.gov/pubmed/33061900
http://dx.doi.org/10.3389/fnhum.2020.00365
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