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From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells

Despite its crucial importance in numerous physiological processes, iron also causes oxidative stress and damage which can promote the growth and proliferation of leukemic cells. Iron metabolism is strictly regulated and the related therapeutic approaches to date have been to restrict iron availabil...

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Detalles Bibliográficos
Autores principales: Grignano, Eric, Birsen, Rudy, Chapuis, Nicolas, Bouscary, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530268/
https://www.ncbi.nlm.nih.gov/pubmed/33042852
http://dx.doi.org/10.3389/fonc.2020.586530

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