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From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells
Despite its crucial importance in numerous physiological processes, iron also causes oxidative stress and damage which can promote the growth and proliferation of leukemic cells. Iron metabolism is strictly regulated and the related therapeutic approaches to date have been to restrict iron availabil...
Autores principales: | Grignano, Eric, Birsen, Rudy, Chapuis, Nicolas, Bouscary, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530268/ https://www.ncbi.nlm.nih.gov/pubmed/33042852 http://dx.doi.org/10.3389/fonc.2020.586530 |
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