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Identification of Drug-Induced Multichannel Block and Proarrhythmic Risk in Humans Using Continuous T Vector Velocity Effect Profiles Derived From Surface Electrocardiograms

We present continuous T vector velocity (TVV) effect profiles as a new method for identifying drug effects on cardiac ventricular repolarization. TVV measures the temporal change in the myocardial action potential distribution during repolarization. The T vector dynamics were measured as the time re...

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Detalles Bibliográficos
Autores principales: Bystricky, Werner, Maier, Christoph, Gintant, Gary, Bergau, Dennis, Carter, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530300/
https://www.ncbi.nlm.nih.gov/pubmed/33071822
http://dx.doi.org/10.3389/fphys.2020.567383