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Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers

Keratin 8 (K8) expressed at the surface of cancer cells, referred as externalized K8 (eK8), has been observed in a variety of carcinoma cell lines. K8 has been previously reported to be expressed in poorly differentiated head and neck squamous cell carcinoma (HNSCC); however, its role during the inv...

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Detalles Bibliográficos
Autores principales: Albaret, Marie Alexandra, Paré, Arnaud, Malet, Lucie, De Souza, Geneviève, Lavergne, Emilie, Goga, Dominique, De Pinieux, Gonzague, Castellier, Claire, Swalduz, Aurélie, Robin, Vivian, Lavergne, Vincent, Mertani, Hichem-Claude, Treilleux, Isabelle, Vermot-Desroches, Claudine, Diaz, Jean-Jacques, Saintigny, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530345/
https://www.ncbi.nlm.nih.gov/pubmed/33010552
http://dx.doi.org/10.1016/j.tranon.2020.100878