A systematic mutational analysis identifies a 5‐residue proline tag that enhances the in vivo immunogenicity of a non‐immunogenic model protein

Poor immunogenicity of small proteins is a major hurdle in developing vaccines or producing antibodies for biopharmaceutical usage. Here, we systematically analyzed the effects of 10 solubility controlling peptide tags (SCP‐tags) on the immunogenicity of a non‐immunogenic model protein, bovine pancr...

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Detalles Bibliográficos
Autores principales: Rahman, Nafsoon, Islam, Mohammad Monirul, Kibria, Md. Golam, Unzai, Satoru, Kuroda, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530378/
https://www.ncbi.nlm.nih.gov/pubmed/33017095
http://dx.doi.org/10.1002/2211-5463.12941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530378/
https://www.ncbi.nlm.nih.gov/pubmed/33017095
http://dx.doi.org/10.1002/2211-5463.12941

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