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Trifluoperazine induces cellular apoptosis by inhibiting autophagy and targeting NUPR1 in multiple myeloma

Multiple myeloma (MM) is the second most common hematologic malignancy of immunoglobulin‐secreting plasma cells. Recent modern combination therapies have improved survival rates, but many patients develop resistance to novel drugs, leading to relapse. Trifluoperazine (TFP), a typical antipsychotic d...

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Detalles Bibliográficos
Autores principales: Li, Anmao, Chen, Xuanxin, Jing, Zizi, Chen, Jianbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530380/
https://www.ncbi.nlm.nih.gov/pubmed/32810364
http://dx.doi.org/10.1002/2211-5463.12960