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Expression of genes involved in drug metabolism differs between perfusable 3D liver tissue and conventional 2D‐cultured hepatocellular carcinoma cells

Tubular 3D liver tissue with enhanced capillary‐like structures branching from a large main channel is potentially useful for drug discovery because the perfusable main channel and capillary‐like structures enable mass transfer into and out from the tissue. Tubular liver tissue is comprised of the h...

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Detalles Bibliográficos
Autores principales: Mori, Nobuhito, Kida, Yasuyuki S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530396/
https://www.ncbi.nlm.nih.gov/pubmed/32794647
http://dx.doi.org/10.1002/2211-5463.12948