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Detection of Phosphorylated Alpha-Synuclein in the Muscularis Propria of the Gastrointestinal Tract Is a Sensitive Predictor for Parkinson's Disease
BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor impairments, including constipation. Lewy bodies and neurites, the pathological hallmarks of PD, are found in the enteric nervous system (ENS) as well as the central nervous system. Constipa...
Autores principales: | Beck, Goichi, Hori, Yumiko, Hayashi, Yoshito, Morii, Eiichi, Takehara, Tetsuo, Mochizuki, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530470/ https://www.ncbi.nlm.nih.gov/pubmed/33029342 http://dx.doi.org/10.1155/2020/4687530 |
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