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Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence

BACKGROUND: Malignant lymphomas of the breast are rare and can be primary or secondary. Non-Hodgkin Lymphoma involving the breast is even rarer comprising 0.04-0.5% of all breast malignancies (Takemura). The incidence is even lower for T-cell lymphomas compared with B-cell subtype. We report the rar...

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Autores principales: Afridi, Faryal, Ruben, Garry D., Oristian, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530482/
https://www.ncbi.nlm.nih.gov/pubmed/33029443
http://dx.doi.org/10.1155/2020/6927835
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author Afridi, Faryal
Ruben, Garry D.
Oristian, Eric
author_facet Afridi, Faryal
Ruben, Garry D.
Oristian, Eric
author_sort Afridi, Faryal
collection PubMed
description BACKGROUND: Malignant lymphomas of the breast are rare and can be primary or secondary. Non-Hodgkin Lymphoma involving the breast is even rarer comprising 0.04-0.5% of all breast malignancies (Takemura). The incidence is even lower for T-cell lymphomas compared with B-cell subtype. We report the rare incidence of primary T-cell lymphoma involving both breast and ipsilateral axilla. CASE: This is the case of an 80-year-old female who initially presented with asymmetry of her right breast. Initial mammograms were inconclusive. MRI could not be performed due to the patient's severe claustrophobia. The patient was then lost to follow-up but re-presented with a new palpable density in the same breast. Subsequent mammogram showed a suspicious lesion with suspicious right axillary lymphadenopathy. Core biopsy was consistent with T-cell lymphoproliferative disorder involving both the breast and the axilla. She was then referred to medical oncology for management. CONCLUSION: Although rare, lymphoproliferative disorders of the breast can be encountered during workup for suspicious breast lesions. It is imperative that the surgeon is aware of this rare diagnosis to facilitate appropriate therapeutic intervention.
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spelling pubmed-75304822020-10-06 Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence Afridi, Faryal Ruben, Garry D. Oristian, Eric Case Rep Surg Case Report BACKGROUND: Malignant lymphomas of the breast are rare and can be primary or secondary. Non-Hodgkin Lymphoma involving the breast is even rarer comprising 0.04-0.5% of all breast malignancies (Takemura). The incidence is even lower for T-cell lymphomas compared with B-cell subtype. We report the rare incidence of primary T-cell lymphoma involving both breast and ipsilateral axilla. CASE: This is the case of an 80-year-old female who initially presented with asymmetry of her right breast. Initial mammograms were inconclusive. MRI could not be performed due to the patient's severe claustrophobia. The patient was then lost to follow-up but re-presented with a new palpable density in the same breast. Subsequent mammogram showed a suspicious lesion with suspicious right axillary lymphadenopathy. Core biopsy was consistent with T-cell lymphoproliferative disorder involving both the breast and the axilla. She was then referred to medical oncology for management. CONCLUSION: Although rare, lymphoproliferative disorders of the breast can be encountered during workup for suspicious breast lesions. It is imperative that the surgeon is aware of this rare diagnosis to facilitate appropriate therapeutic intervention. Hindawi 2020-09-22 /pmc/articles/PMC7530482/ /pubmed/33029443 http://dx.doi.org/10.1155/2020/6927835 Text en Copyright © 2020 Faryal Afridi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Afridi, Faryal
Ruben, Garry D.
Oristian, Eric
Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence
title Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence
title_full Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence
title_fullStr Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence
title_full_unstemmed Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence
title_short Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence
title_sort case of primary breast and ipsilateral axillary t-cell lymphoma: a rare occurrence
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530482/
https://www.ncbi.nlm.nih.gov/pubmed/33029443
http://dx.doi.org/10.1155/2020/6927835
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