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Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest

Objective: This study aimed to retrospectively investigate the clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest. Patients and Methods: All drowning patients who were transported to our department from January 2011 to December 2019 were ret...

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Autores principales: Muramatsu, Ken-ichi, Omori, Kazuhiko, Kushida, Yoshihiro, Nagasawa, Hiroki, Takeuchi, Ikuto, Jitsuiki, Kei, Shitara, Jun, Ohsaka, Hiromichi, Oode, Yasumasa, Yanagawa, Youichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Association of Rural Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530585/
https://www.ncbi.nlm.nih.gov/pubmed/33033542
http://dx.doi.org/10.2185/jrm.2020-012
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author Muramatsu, Ken-ichi
Omori, Kazuhiko
Kushida, Yoshihiro
Nagasawa, Hiroki
Takeuchi, Ikuto
Jitsuiki, Kei
Shitara, Jun
Ohsaka, Hiromichi
Oode, Yasumasa
Yanagawa, Youichi
author_facet Muramatsu, Ken-ichi
Omori, Kazuhiko
Kushida, Yoshihiro
Nagasawa, Hiroki
Takeuchi, Ikuto
Jitsuiki, Kei
Shitara, Jun
Ohsaka, Hiromichi
Oode, Yasumasa
Yanagawa, Youichi
author_sort Muramatsu, Ken-ichi
collection PubMed
description Objective: This study aimed to retrospectively investigate the clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest. Patients and Methods: All drowning patients who were transported to our department from January 2011 to December 2019 were retrospectively investigated through a medical chart review and included as subjects in the present study. The exclusion criteria were the occurrence of cardiac arrest before patient arrival to our department and lack of measurement of the fibrin degradation product level on arrival. The subjects were divided into two groups: early discharge group, which included patients who were discharged within 3 days, and late discharge group, which included patients who were discharged after 3 days. Results: The early discharge group included 10 subjects and the late discharge group included 39 subjects. No significant differences were observed in age, sex, proportion of freshwater drowning cases, proportion of alcohol drinkers, vital signs, blood gas analysis findings, proportion of lung lesions, or survival rate between the two groups. The levels of glucose and fibrin degradation products on arrival were significantly greater in the early discharge group than in the late discharge group. A multivariate analysis showed that the only significant predictor of early discharge was the fibrin degradation product level among variables identified in a univariate analysis. Conclusion: This is the first study to show that the level of fibrin degradation products on arrival can predict early or late discharge in drowning patients without cardiac arrest before arriving to the hospital.
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spelling pubmed-75305852020-10-07 Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest Muramatsu, Ken-ichi Omori, Kazuhiko Kushida, Yoshihiro Nagasawa, Hiroki Takeuchi, Ikuto Jitsuiki, Kei Shitara, Jun Ohsaka, Hiromichi Oode, Yasumasa Yanagawa, Youichi J Rural Med Original Article Objective: This study aimed to retrospectively investigate the clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest. Patients and Methods: All drowning patients who were transported to our department from January 2011 to December 2019 were retrospectively investigated through a medical chart review and included as subjects in the present study. The exclusion criteria were the occurrence of cardiac arrest before patient arrival to our department and lack of measurement of the fibrin degradation product level on arrival. The subjects were divided into two groups: early discharge group, which included patients who were discharged within 3 days, and late discharge group, which included patients who were discharged after 3 days. Results: The early discharge group included 10 subjects and the late discharge group included 39 subjects. No significant differences were observed in age, sex, proportion of freshwater drowning cases, proportion of alcohol drinkers, vital signs, blood gas analysis findings, proportion of lung lesions, or survival rate between the two groups. The levels of glucose and fibrin degradation products on arrival were significantly greater in the early discharge group than in the late discharge group. A multivariate analysis showed that the only significant predictor of early discharge was the fibrin degradation product level among variables identified in a univariate analysis. Conclusion: This is the first study to show that the level of fibrin degradation products on arrival can predict early or late discharge in drowning patients without cardiac arrest before arriving to the hospital. The Japanese Association of Rural Medicine 2020-10-01 2020-10 /pmc/articles/PMC7530585/ /pubmed/33033542 http://dx.doi.org/10.2185/jrm.2020-012 Text en ©2020 The Japanese Association of Rural Medicine http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Original Article
Muramatsu, Ken-ichi
Omori, Kazuhiko
Kushida, Yoshihiro
Nagasawa, Hiroki
Takeuchi, Ikuto
Jitsuiki, Kei
Shitara, Jun
Ohsaka, Hiromichi
Oode, Yasumasa
Yanagawa, Youichi
Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest
title Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest
title_full Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest
title_fullStr Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest
title_full_unstemmed Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest
title_short Clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest
title_sort clinical significance of the level of fibrin degradation products in drowning patients without cardiac arrest
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530585/
https://www.ncbi.nlm.nih.gov/pubmed/33033542
http://dx.doi.org/10.2185/jrm.2020-012
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