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Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine

There is a large unmet need for a prophylactic hepatitis C virus (HCV) vaccine to control the ongoing epidemic with this deadly pathogen. Many antiviral vaccines employ whole viruses as antigens. For HCV, this approach became feasible following the development of infectious cell culture systems for...

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Detalles Bibliográficos
Autores principales: Lothert, Keven, Offersgaard, Anna F., Pihl, Anne F., Mathiesen, Christian K., Jensen, Tanja B., Alzua, Garazi Peña, Fahnøe, Ulrik, Bukh, Jens, Gottwein, Judith M., Wolff, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530675/
https://www.ncbi.nlm.nih.gov/pubmed/33004836
http://dx.doi.org/10.1038/s41598-020-72328-5