Cargando…

BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer

Inflammation might substantially contribute to the limited therapeutic success of current systemic therapies in colorectal cancer (CRC). Amongst cytokines involved in CRC biology, the proinflammatory chemokine IL-8 has recently emerged as a potential prognostic/predictive biomarker. Here, we show th...

Descripción completa

Detalles Bibliográficos
Autores principales: Conciatori, Fabiana, Bazzichetto, Chiara, Amoreo, Carla Azzurra, Sperduti, Isabella, Donzelli, Sara, Diodoro, Maria Grazia, Buglioni, Simonetta, Falcone, Italia, Shirasawa, Senji, Blandino, Giovanni, Ferretti, Gianluigi, Cognetti, Francesco, Milella, Michele, Ciuffreda, Ludovica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530707/
https://www.ncbi.nlm.nih.gov/pubmed/33004975
http://dx.doi.org/10.1038/s42003-020-01263-y