Cargando…

Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis

The nuclear factor kappa beta (NFκB) signaling pathway plays an important role in liver homeostasis and cancer development. Tax1-binding protein 1 (Tax1BP1) is a regulator of the NFκB signaling pathway, but its role in the liver and hepatocellular carcinoma (HCC) is presently unknown. Here we invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	Waidmann, Oliver, Pleli, Thomas, Weigert, Andreas, Imelmann, Esther, Kakoschky, Bianca, Schmithals, Christian, Döring, Claudia, Frank, Matthias, Longerich, Thomas, Köberle, Verena, Hansmann, Martin-Leo, Brüne, Bernhard, Zeuzem, Stefan, Piiper, Albrecht, Dikic, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530720/ https://www.ncbi.nlm.nih.gov/pubmed/33004985 http://dx.doi.org/10.1038/s41598-020-73387-4

Ejemplares similares

Selective targeting of tumor associated macrophages in different tumor models
por: Kakoschky, Bianca, et al.
Publicado: (2018)

Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers
por: Köberle, Verena, et al.
Publicado: (2013)

Serum MicroRNA-122 Predicts Survival in Patients with Liver Cirrhosis
por: Waidmann, Oliver, et al.
Publicado: (2012)

Serum Autotaxin Is a Parameter for the Severity of Liver Cirrhosis and Overall Survival in Patients with Liver Cirrhosis – A Prospective Cohort Study
por: Pleli, Thomas, et al.
Publicado: (2014)

MicroRNA Profiling of Laser-Microdissected Hepatocellular Carcinoma Reveals an Oncogenic Phenotype of the Tumor Capsule()()()
por: Peveling-Oberhag, Jan, et al.
Publicado: (2014)

Assessment of the Pharmacokinetics, Disposition, and Duration of Action of the Tumour-Targeting Peptide CEND-1
por: Järveläinen, Harri A., et al.
Publicado: (2023)

Serum sphingolipidomic analyses reveal an upregulation of C16- ceramide and sphingosine-1-phosphate in hepatocellular carcinoma
por: Grammatikos, Georgios, et al.
Publicado: (2016)

Theranostic Sorafenib-Loaded Polymeric Nanocarriers Manufactured by Enhanced Gadolinium Conjugation Techniques
por: Feczkó, Tivadar, et al.
Publicado: (2019)

Low 25-Hydroxyvitamin D Levels Are Associated with Infections and Mortality in Patients with Cirrhosis
por: Finkelmeier, Fabian, et al.
Publicado: (2015)

Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury
por: Scheiermann, Patrick, et al.
Publicado: (2015)

The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC‐II molecules
por: Sarango, Gabriela, et al.
Publicado: (2022)

Analysis of the TAX1BP1 gene in head and neck cancer patients
por: Ruiz, Mariangela Torreglosa, et al.
Publicado: (2015)

Commensal Microbiota Contributes to Chronic Endocarditis in TAX1BP1 Deficient Mice
por: Nakano, Satoko, et al.
Publicado: (2013)

Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1
por: Matsushita, Nobuko, et al.
Publicado: (2016)

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study
por: Kronenberger, Bernd, et al.
Publicado: (2012)

NRP/Optineurin Cooperates with TAX1BP1 to Potentiate the Activation of NF-κB by Human T-Lymphotropic Virus Type 1 Tax Protein
por: Journo, Chloé, et al.
Publicado: (2009)

Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair
por: Plotz, Guido, et al.
Publicado: (2006)

Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation
por: Turco, Eleonora, et al.
Publicado: (2021)

PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles
por: Fan, Yinzhen, et al.
Publicado: (2022)

The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy
por: Tumbarello, David A., et al.
Publicado: (2015)

Circulating hypoxia marker carbonic anhydrase IX (CA9) in patients with hepatocellular carcinoma and patients with cirrhosis
por: Finkelmeier, Fabian, et al.
Publicado: (2018)

Correction: The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy
por: Tumbarello, David A., et al.
Publicado: (2016)

Serum MicroRNA-21 as Marker for Necroinflammation in Hepatitis C Patients with and without Hepatocellular Carcinoma
por: Bihrer, Verena, et al.
Publicado: (2011)

Oncogene-dependent function of BRG1 in hepatocarcinogenesis
por: Wang, Pan, et al.
Publicado: (2020)

The human T-cell leukemia virus type I (HTLV-I) oncoprotein Tax promotes persistent NF-κB activation by blocking the phosphorylation of the adaptor molecule TAX1BP
por: Shembade, Noula, et al.
Publicado: (2011)

Alcohol and hepatocarcinogenesis
por: Taniai, Makiko
Publicado: (2020)

Hepatic B cell leukemia-3 suppresses chemically-induced hepatocarcinogenesis in mice through altered MAPK and NF-κB activation
por: Gehrke, Nadine, et al.
Publicado: (2016)

Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages
por: Bell, Samantha L., et al.
Publicado: (2021)

NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis
por: Luiken, Sarah, et al.
Publicado: (2020)

Sphingosine-1-Phosphate and Macrophage Biology—How the Sphinx Tames the Big Eater
por: Weigert, Andreas, et al.
Publicado: (2019)

BRG1 promotes hepatocarcinogenesis by regulating proliferation and invasiveness
por: Kaufmann, Benedikt, et al.
Publicado: (2017)

Keep a Little Fire Burning—The Delicate Balance of Targeting Sphingosine-1-Phosphate in Cancer Immunity
por: Olesch, Catherine, et al.
Publicado: (2022)

Soluble Serum CD81 Is Elevated in Patients with Chronic Hepatitis C and Correlates with Alanine Aminotransferase Serum Activity
por: Welker, Martin-Walter, et al.
Publicado: (2012)

The HTLV-1 Tax interactome
por: Boxus, Mathieu, et al.
Publicado: (2008)

GLUTATHIONE S‐TRANSFERASES AND HEPATOCARCINOGENESIS
por: Sato, Kiyomi
Publicado: (1988)

Oxidative stress and hepatocarcinogenesis
por: Fu, Ying, et al.
Publicado: (2018)

TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses
por: Yang, Qing, et al.
Publicado: (2017)

Beyond Immune Cell Migration: The Emerging Role of the Sphingosine-1-phosphate Receptor S1PR4 as a Modulator of Innate Immune Cell Activation
por: Olesch, Catherine, et al.
Publicado: (2017)

S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1β or Lipocalin-2
por: Syed, Shahzad N., et al.
Publicado: (2017)

The importance of ubiquitination and sumoylation on the transforming activity of HTLV Tax-1 and Tax-2
por: Zane, Linda, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2vvj0bacm0br1elvak37j88dd4