SecY-mediated quality control prevents the translocation of non-gated porins

OmpC and OmpF are among the most abundant outer membrane proteins in E. coli and serve as hydrophilic channels to mediate uptake of small molecules including antibiotics. Influx selectivity is controlled by the so-called constriction zone or eyelet of the channel. Mutations in the loop domain formin...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Sebastian, Bader, Verian, Natriashvili, Ana, Koch, Hans-Georg, Winklhofer, Konstanze F., Tatzelt, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530735/
https://www.ncbi.nlm.nih.gov/pubmed/33004891
http://dx.doi.org/10.1038/s41598-020-73185-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530735/
https://www.ncbi.nlm.nih.gov/pubmed/33004891
http://dx.doi.org/10.1038/s41598-020-73185-y

Ejemplares similares