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SecY-mediated quality control prevents the translocation of non-gated porins
OmpC and OmpF are among the most abundant outer membrane proteins in E. coli and serve as hydrophilic channels to mediate uptake of small molecules including antibiotics. Influx selectivity is controlled by the so-called constriction zone or eyelet of the channel. Mutations in the loop domain formin...
Autores principales: | Jung, Sebastian, Bader, Verian, Natriashvili, Ana, Koch, Hans-Georg, Winklhofer, Konstanze F., Tatzelt, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530735/ https://www.ncbi.nlm.nih.gov/pubmed/33004891 http://dx.doi.org/10.1038/s41598-020-73185-y |
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