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SENP7 knockdown inhibited pyroptosis and NF-κB/NLRP3 inflammasome pathway activation in Raw 264.7 cells

Pyroptosis is a kind of necrotic and inflammatory programmed cell death induced by inflammatory caspases. SENP7 is a SUMO-specific protease, which mainly acts on deconjugation of SUMOs from substrate proteins. We evaluated the effect of SENP7 knockdown on pyroptosis, NF-κB signaling pathway, and NLR...

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Detalles Bibliográficos
Autores principales:	Li, Xun, Jiao, Fangzhou, Hong, Jia, Yang, Fan, Wang, Luwen, Gong, Zuojiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530744/ https://www.ncbi.nlm.nih.gov/pubmed/33004957 http://dx.doi.org/10.1038/s41598-020-73400-w

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