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Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of bla(TEM-1B)

A phenotype of Escherichia coli and Klebsiella pneumoniae, resistant to piperacillin/tazobactam (TZP) but susceptible to carbapenems and 3rd generation cephalosporins, has emerged. The resistance mechanism associated with this phenotype has been identified as hyperproduction of the β-lactamase TEM....

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Detalles Bibliográficos
Autores principales: Hubbard, Alasdair T. M., Mason, Jenifer, Roberts, Paul, Parry, Christopher M., Corless, Caroline, van Aartsen, Jon, Howard, Alex, Bulgasim, Issra, Fraser, Alice J., Adams, Emily R., Roberts, Adam P., Edwards, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530762/
https://www.ncbi.nlm.nih.gov/pubmed/33004811
http://dx.doi.org/10.1038/s41467-020-18668-2