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Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of bla(TEM-1B)
A phenotype of Escherichia coli and Klebsiella pneumoniae, resistant to piperacillin/tazobactam (TZP) but susceptible to carbapenems and 3rd generation cephalosporins, has emerged. The resistance mechanism associated with this phenotype has been identified as hyperproduction of the β-lactamase TEM....
Autores principales: | Hubbard, Alasdair T. M., Mason, Jenifer, Roberts, Paul, Parry, Christopher M., Corless, Caroline, van Aartsen, Jon, Howard, Alex, Bulgasim, Issra, Fraser, Alice J., Adams, Emily R., Roberts, Adam P., Edwards, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530762/ https://www.ncbi.nlm.nih.gov/pubmed/33004811 http://dx.doi.org/10.1038/s41467-020-18668-2 |
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