Efficacy and Safety of Nivolumab Plus Ipilimumab in Patients With Advanced Hepatocellular Carcinoma Previously Treated With Sorafenib: The CheckMate 040 Randomized Clinical Trial

IMPORTANCE: Most patients with hepatocellular carcinoma (HCC) are diagnosed with advanced disease not eligible for potentially curative therapies; therefore, new treatment options are needed. Combining nivolumab with ipilimumab may improve clinical outcomes compared with nivolumab monotherapy. OBJEC...

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Detalles Bibliográficos
Autores principales: Yau, Thomas, Kang, Yoon-Koo, Kim, Tae-You, El-Khoueiry, Anthony B., Santoro, Armando, Sangro, Bruno, Melero, Ignacio, Kudo, Masatoshi, Hou, Ming-Mo, Matilla, Ana, Tovoli, Francesco, Knox, Jennifer J., Ruth He, Aiwu, El-Rayes, Bassel F., Acosta-Rivera, Mirelis, Lim, Ho-Yeong, Neely, Jaclyn, Shen, Yun, Wisniewski, Tami, Anderson, Jeffrey, Hsu, Chiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530824/
https://www.ncbi.nlm.nih.gov/pubmed/33001135
http://dx.doi.org/10.1001/jamaoncol.2020.4564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530824/
https://www.ncbi.nlm.nih.gov/pubmed/33001135
http://dx.doi.org/10.1001/jamaoncol.2020.4564

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