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Tadalafil may improve cerebral perfusion in small-vessel occlusion stroke—a pilot study
New treatments for cerebral small-vessel disease are needed to reduce the risk of small-vessel occlusion stroke and vascular cognitive impairment. We investigated an approach targeted to the signalling molecule cyclic guanosine monophosphate, using the phosphodiesterase 5 inhibitor tadalafil, to exp...
Autores principales: | Ölmestig, Joakim, Marlet, Ida R, Hansen, Rasmus H, Rehman, Shazia, Krawcyk, Rikke Steen, Rostrup, Egill, Lambertsen, Kate L, Kruuse, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530832/ https://www.ncbi.nlm.nih.gov/pubmed/33033800 http://dx.doi.org/10.1093/braincomms/fcaa020 |
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