Cargando…
Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos
[Image: see text] Many reagents have emerged to study the function of specific enzymes in vitro. On the other hand, target specific reagents are scarce or need improvement, allowing investigations of the function of individual enzymes in their native cellular context. Here we report the development...
Autores principales: | Kooij, Raymond, Liu, Sijia, Sapmaz, Aysegul, Xin, Bo-Tao, Janssen, George M. C., van Veelen, Peter A., Ovaa, Huib, Dijke, Peter ten, Geurink, Paul P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530896/ https://www.ncbi.nlm.nih.gov/pubmed/32886496 http://dx.doi.org/10.1021/jacs.0c07726 |
Ejemplares similares
-
Chemical Toolkit
for PARK7: Potent, Selective, and
High-Throughput
por: Jia, Yuqing, et al.
Publicado: (2022) -
Overexpression of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in boys with cryptorchidism
por: Toliczenko-Bernatowicz, Dorota, et al.
Publicado: (2018) -
Development of a DUB-selective fluorogenic substrate
por: Gjonaj, Lorina, et al.
Publicado: (2019) -
Catching a DUB in the act: novel ubiquitin-based active site directed probes
por: Ekkebus, Reggy, et al.
Publicado: (2014) -
Highlighting the Proteasome: Using Fluorescence to Visualize Proteasome Activity and Distribution
por: Gan, Jin, et al.
Publicado: (2019)