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Hidden Microatelectases Increase Vulnerability to Ventilation-Induced Lung Injury
Mechanical ventilation of lungs suffering from microatelectases may trigger the development of acute lung injury (ALI). Direct lung injury by bleomycin results in surfactant dysfunction and microatelectases at day 1 while tissue elastance and oxygenation remain normal. Computational simulations of a...
Autores principales: | Albert, Karolin, Krischer, Jeanne-Marie, Pfaffenroth, Alexander, Wilde, Sabrina, Lopez-Rodriguez, Elena, Braun, Armin, Smith, Bradford J., Knudsen, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530907/ https://www.ncbi.nlm.nih.gov/pubmed/33071807 http://dx.doi.org/10.3389/fphys.2020.530485 |
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