Genetically-regulated transcriptomics & copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestry

BACKGROUND: Proctitis is an inflammation of the rectum and may be induced by radiation treatment for cancer. The genetic heritability of developing radiotoxicity and prior role of genetic variants as being associated with side-effects of radiotherapy necessitates further investigation for underlying...

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Detalles Bibliográficos
Autores principales: Pathak, Gita A., Polimanti, Renato, Silzer, Talisa K., Wendt, Frank R., Chakraborty, Ranajit, Phillips, Nicole R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530964/
https://www.ncbi.nlm.nih.gov/pubmed/33008348
http://dx.doi.org/10.1186/s12885-020-07457-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530964/
https://www.ncbi.nlm.nih.gov/pubmed/33008348
http://dx.doi.org/10.1186/s12885-020-07457-1

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