Cargando…

Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface

BACKGROUND: Ross River virus (RRV) is responsible for the most common vector-borne disease of humans reported in Australia. The virus circulates in enzootic cycles between multiple species of mosquitoes, wildlife reservoir hosts and humans. Public health concern about RRV is increasing due to rising...

Descripción completa

Detalles Bibliográficos
Autores principales: Murphy, Amanda K., Clennon, Julie A., Vazquez-Prokopec, Gonzalo, Jansen, Cassie C., Frentiu, Francesca D., Hafner, Louise M., Hu, Wenbiao, Devine, Gregor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530966/
https://www.ncbi.nlm.nih.gov/pubmed/33008314
http://dx.doi.org/10.1186/s12879-020-05411-x
_version_ 1783589671512571904
author Murphy, Amanda K.
Clennon, Julie A.
Vazquez-Prokopec, Gonzalo
Jansen, Cassie C.
Frentiu, Francesca D.
Hafner, Louise M.
Hu, Wenbiao
Devine, Gregor J.
author_facet Murphy, Amanda K.
Clennon, Julie A.
Vazquez-Prokopec, Gonzalo
Jansen, Cassie C.
Frentiu, Francesca D.
Hafner, Louise M.
Hu, Wenbiao
Devine, Gregor J.
author_sort Murphy, Amanda K.
collection PubMed
description BACKGROUND: Ross River virus (RRV) is responsible for the most common vector-borne disease of humans reported in Australia. The virus circulates in enzootic cycles between multiple species of mosquitoes, wildlife reservoir hosts and humans. Public health concern about RRV is increasing due to rising incidence rates in Australian urban centres, along with increased circulation in Pacific Island countries. Australia experienced its largest recorded outbreak of 9544 cases in 2015, with the majority reported from south east Queensland (SEQ). This study examined potential links between disease patterns and transmission pathways of RRV. METHODS: The spatial and temporal distribution of notified RRV cases, and associated epidemiological features in SEQ, were analysed for the period 2001–2016. This included fine-scale analysis of disease patterns across the suburbs of the capital city of Brisbane, and those of 8 adjacent Local Government Areas, and host spot analyses to identify locations with significantly high incidence. RESULTS: The mean annual incidence rate for the region was 41/100,000 with a consistent seasonal peak in cases between February and May. The highest RRV incidence was in adults aged from 30 to 64 years (mean incidence rate: 59/100,000), and females had higher incidence rates than males (mean incidence rates: 44/100,000 and 34/100,000, respectively). Spatial patterns of disease were heterogeneous between years, and there was a wide distribution of disease across both urban and rural areas of SEQ. Overall, the highest incidence rates were reported from predominantly rural suburbs to the north of Brisbane City, with significant hot spots located in peri-urban suburbs where residential, agricultural and conserved natural land use types intersect. CONCLUSIONS: Although RRV is endemic across all of SEQ, transmission is most concentrated in areas where urban and peri-urban environments intersect. The drivers of RRV transmission across rural-urban landscapes should be prioritised for further investigation, including identification of specific vectors and hosts that mediate human spillover.
format Online
Article
Text
id pubmed-7530966
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-75309662020-10-02 Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface Murphy, Amanda K. Clennon, Julie A. Vazquez-Prokopec, Gonzalo Jansen, Cassie C. Frentiu, Francesca D. Hafner, Louise M. Hu, Wenbiao Devine, Gregor J. BMC Infect Dis Research Article BACKGROUND: Ross River virus (RRV) is responsible for the most common vector-borne disease of humans reported in Australia. The virus circulates in enzootic cycles between multiple species of mosquitoes, wildlife reservoir hosts and humans. Public health concern about RRV is increasing due to rising incidence rates in Australian urban centres, along with increased circulation in Pacific Island countries. Australia experienced its largest recorded outbreak of 9544 cases in 2015, with the majority reported from south east Queensland (SEQ). This study examined potential links between disease patterns and transmission pathways of RRV. METHODS: The spatial and temporal distribution of notified RRV cases, and associated epidemiological features in SEQ, were analysed for the period 2001–2016. This included fine-scale analysis of disease patterns across the suburbs of the capital city of Brisbane, and those of 8 adjacent Local Government Areas, and host spot analyses to identify locations with significantly high incidence. RESULTS: The mean annual incidence rate for the region was 41/100,000 with a consistent seasonal peak in cases between February and May. The highest RRV incidence was in adults aged from 30 to 64 years (mean incidence rate: 59/100,000), and females had higher incidence rates than males (mean incidence rates: 44/100,000 and 34/100,000, respectively). Spatial patterns of disease were heterogeneous between years, and there was a wide distribution of disease across both urban and rural areas of SEQ. Overall, the highest incidence rates were reported from predominantly rural suburbs to the north of Brisbane City, with significant hot spots located in peri-urban suburbs where residential, agricultural and conserved natural land use types intersect. CONCLUSIONS: Although RRV is endemic across all of SEQ, transmission is most concentrated in areas where urban and peri-urban environments intersect. The drivers of RRV transmission across rural-urban landscapes should be prioritised for further investigation, including identification of specific vectors and hosts that mediate human spillover. BioMed Central 2020-10-02 /pmc/articles/PMC7530966/ /pubmed/33008314 http://dx.doi.org/10.1186/s12879-020-05411-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Murphy, Amanda K.
Clennon, Julie A.
Vazquez-Prokopec, Gonzalo
Jansen, Cassie C.
Frentiu, Francesca D.
Hafner, Louise M.
Hu, Wenbiao
Devine, Gregor J.
Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface
title Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface
title_full Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface
title_fullStr Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface
title_full_unstemmed Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface
title_short Spatial and temporal patterns of Ross River virus in south east Queensland, Australia: identification of hot spots at the rural-urban interface
title_sort spatial and temporal patterns of ross river virus in south east queensland, australia: identification of hot spots at the rural-urban interface
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530966/
https://www.ncbi.nlm.nih.gov/pubmed/33008314
http://dx.doi.org/10.1186/s12879-020-05411-x
work_keys_str_mv AT murphyamandak spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface
AT clennonjuliea spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface
AT vazquezprokopecgonzalo spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface
AT jansencassiec spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface
AT frentiufrancescad spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface
AT hafnerlouisem spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface
AT huwenbiao spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface
AT devinegregorj spatialandtemporalpatternsofrossrivervirusinsoutheastqueenslandaustraliaidentificationofhotspotsattheruralurbaninterface