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Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans

Maternal mRNA clearance is an essential process that occurs during maternal-to-zygotic transition (MZT). However, the dynamics, functional importance, and pathological relevance of maternal mRNA decay in human preimplantation embryos have not yet been analyzed. Here we report the zygotic genome acti...

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Detalles Bibliográficos
Autores principales: Sha, Qian-Qian, Zheng, Wei, Wu, Yun-Wen, Li, Sen, Guo, Lei, Zhang, Shuoping, Lin, Ge, Ou, Xiang-Hong, Fan, Heng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530992/
https://www.ncbi.nlm.nih.gov/pubmed/33004802
http://dx.doi.org/10.1038/s41467-020-18680-6

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