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Matrix Metalloproteinase-12 Is Required for Granuloma Progression

BACKGROUND: Sarcoidosis is a chronic inflammatory disease of unknown cause characterized by granuloma formation. Mechanisms for chronic persistence of granulomas are unknown. Matrix Metalloproteinase-12 (MMP12) degrades extracellular matrix elastin and enables infiltration of immune cells responsibl...

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Detalles Bibliográficos
Autores principales:	Mohan, Arjun, Neequaye, Nicole, Malur, Anagha, Soliman, Eman, McPeek, Matthew, Leffler, Nancy, Ogburn, David, Tokarz, Debra A., Knudson, Warren, Gharib, Sina A., Schnapp, Lynn M., Barna, Barbara P., Thomassen, Mary Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531023/ https://www.ncbi.nlm.nih.gov/pubmed/33072094 http://dx.doi.org/10.3389/fimmu.2020.553949

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