Cargando…

The role of TRPV1 ion channels in the suppression of gastric cancer development

BACKGROUND: Although the aberrant expression and function of most Ca(2+)-permeable channels are known to promote gastrointestinal tumors, the association between transient receptor potential vanilloid receptor 1 (TRPV1) channels and gastric cancer (GC) has not yet been explored. Herein, we sought to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Nannan, Yang, Feng, Chen, Siyuan, Wan, Hanxing, Zhao, Xiaoyan, Dong, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531167/ https://www.ncbi.nlm.nih.gov/pubmed/33008449 http://dx.doi.org/10.1186/s13046-020-01707-7

Ejemplares similares

Different functional roles for K(+) channel subtypes in regulating small intestinal glucose and ion transport
por: Du, Chao, et al.
Publicado: (2019)

Capsaicin inhibits intestinal Cl(-) secretion and promotes Na(+) absorption by blocking TRPV4 channels in healthy and colitic mice
por: Wan, Hanxing, et al.
Publicado: (2022)

Role of TRPV1 ion channel in cervical squamous cell carcinoma genesis
por: Wang, Zhenming, et al.
Publicado: (2022)

Role of Serosal TRPV4-Constituted SOCE Mechanism in Secretagogues-Stimulated Intestinal Epithelial Anion Secretion
por: Cui, Yinghui, et al.
Publicado: (2021)

Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel
por: Zhen, Wenxuan, et al.
Publicado: (2023)

TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation
por: Huang, Susan M, et al.
Publicado: (2011)

Conformational ensemble of the human TRPV3 ion channel
por: Zubcevic, Lejla, et al.
Publicado: (2018)

TRPV3 Ion Channel: From Gene to Pharmacology
por: Kalinovskii, Aleksandr P., et al.
Publicado: (2023)

Molecular basis for heat desensitization of TRPV1 ion channels
por: Luo, Lei, et al.
Publicado: (2019)

Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart
por: Gorbunov, Alexandr S., et al.
Publicado: (2019)

Conformational Plasticity in the Selectivity Filter of the TRPV2 Ion Channel
por: Zubcevic, Lejla, et al.
Publicado: (2018)

The role of TRPV1 channels in atherosclerosis
por: Zhang, Chenyang, et al.
Publicado: (2020)

Cryo-electron microscopy structure of the TRPV2 ion channel
por: Zubcevic, Lejla, et al.
Publicado: (2016)

Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels
por: Ufret-Vincenty, Carmen A., et al.
Publicado: (2015)

TRPV4 is the temperature-sensitive ion channel of human sperm
por: Mundt, Nadine, et al.
Publicado: (2018)

TRPV4: A Physio and Pathophysiologically Significant Ion Channel
por: Rosenbaum, Tamara, et al.
Publicado: (2020)

An Unorthodox Mechanism Underlying Voltage Sensitivity of TRPV1 Ion Channel
por: Yang, Fan, et al.
Publicado: (2020)

NCX1 coupled with TRPC1 to promote gastric cancer via Ca(2+)/AKT/β-catenin pathway
por: Wan, Hanxing, et al.
Publicado: (2022)

Beneficial effect of capsaicin via TRPV4/EDH signals on mesenteric arterioles of normal and colitis mice
por: Zhang, Luyun, et al.
Publicado: (2021)

Structural mechanism underlying capsaicin binding and activation of TRPV1 ion channel
por: Yang, Fan, et al.
Publicado: (2015)

Author Correction: Molecular basis for heat desensitization of TRPV1 ion channels
por: Luo, Lei, et al.
Publicado: (2020)

Molecular mechanism of TRPV2 channel modulation by cannabidiol
por: Pumroy, Ruth A, et al.
Publicado: (2019)

Pathophysiological Roles of the TRPV4 Channel in the Heart
por: Chaigne, Sébastien, et al.
Publicado: (2023)

Structure of the TRPV1 ion channel determined by electron cryo-microscopy
por: Liao, Maofu, et al.
Publicado: (2013)

The ion selectivity filter is not an activation gate in TRPV1-3 channels
por: Jara-Oseguera, Andrés, et al.
Publicado: (2019)

Confined Dynamics of Water in Transmembrane Pore of TRPV1 Ion Channel
por: Trofimov, Yury A., et al.
Publicado: (2019)

Exploring the Ion Channel TRPV2 and Testicular Macrophages in Mouse Testis
por: Eubler, Katja, et al.
Publicado: (2021)

The capsaicin binding affinity of wildtype and mutant TRPV1 ion channels
por: Li, Shisheng, et al.
Publicado: (2023)

Endocannabinoid activation of the TRPV1 ion channel is distinct from activation by capsaicin
por: Li, Yanxin, et al.
Publicado: (2021)

Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel
por: Zhang, Xu-Feng, et al.
Publicado: (2011)

Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel
por: Mo, Xiaoyi, et al.
Publicado: (2022)

Extent of intrinsic disorder and NMR chemical shift assignments of the distal N-termini from human TRPV1, TRPV2 and TRPV3 ion channels
por: Wiedemann, Christoph, et al.
Publicado: (2022)

Role of TRPV1 and TRPA1 Ion Channels in Inflammatory Bowel Diseases: Potential Therapeutic Targets?
por: Csekő, Kata, et al.
Publicado: (2019)

Role of the ion channel, transient receptor potential cation channel subfamily V member 1 (TRPV1), in allergic asthma
por: Baker, Katie, et al.
Publicado: (2016)

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
por: Grandl, Jörg, et al.
Publicado: (2010)

A Novel Ion Channel Formed by Interaction of TRPML3 with TRPV5
por: Guo, Zhaohua, et al.
Publicado: (2013)

Measurement of Ensemble TRPV1 Ion Channel Currents Using Droplet Bilayers
por: Vijayvergiya, Viksita, et al.
Publicado: (2015)

Polymodal Transient Receptor Potential Vanilloid (TRPV) Ion Channels in Chondrogenic Cells
por: Szűcs Somogyi, Csilla, et al.
Publicado: (2015)

Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes
por: Zubcevic, Lejla, et al.
Publicado: (2019)

TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel
por: Toft-Bertelsen, Trine L., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oiukfnk3uupmp68o4encl0pb1p