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AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
Lactate is used as an energy source by producer cells or shuttled to neighboring cells and tissues. Both glucose and lactate fulfill the bioenergetic demand of neurons, the latter imported from astrocytes. The contribution of astrocytic lactate to neuronal bioenergetics and the mechanisms of astrocy...
Autores principales: | Muraleedharan, Ranjithmenon, Gawali, Mruniya V., Tiwari, Durgesh, Sukumaran, Abitha, Oatman, Nicole, Anderson, Jane, Nardini, Diana, Bhuiyan, Mohammad Alfrad Nobel, Tkáč, Ivan, Ward, Amber Lynne, Kundu, Mondira, Waclaw, Ronald, Chow, Lionel M., Gross, Christina, Rao, Raghavendra, Schirmeier, Stefanie, Dasgupta, Biplab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531170/ https://www.ncbi.nlm.nih.gov/pubmed/32877674 http://dx.doi.org/10.1016/j.celrep.2020.108092 |
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