Crystallization and structure of ebselen bound to Cys141 of human inositol monophosphatase

Inositol monophosphatase (IMPase) is inhibited by lithium, which is the most efficacious treatment for bipolar disorder. Several therapies have been approved, or are going through clinical trials, aimed at the replacement of lithium in the treatment of bipolar disorder. One candidate small molecule...

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Detalles Bibliográficos
Autores principales: Fenn, Gareth D., Waller-Evans, Helen, Atack, John R., Bax, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531247/
https://www.ncbi.nlm.nih.gov/pubmed/33006574
http://dx.doi.org/10.1107/S2053230X20011310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531247/
https://www.ncbi.nlm.nih.gov/pubmed/33006574
http://dx.doi.org/10.1107/S2053230X20011310

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