Plasma-Based Longitudinal Evaluation of ESR1 Epigenetic Status in Hormone Receptor-Positive HER2-Negative Metastatic Breast Cancer

BACKGROUND: Endocrine therapy (ET) is the mainstay of treatment for hormone receptor-positive human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer; however, adaptive mechanisms emerge in about 25–30% of cases through alterations in the estrogen receptor ligand-binding do...

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Detalles Bibliográficos
Autores principales: Gerratana, Lorenzo, Basile, Debora, Franzoni, Alessandra, Allegri, Lorenzo, Viotto, Davide, Corvaja, Carla, Bortot, Lucia, Bertoli, Elisa, Buriolla, Silvia, Targato, Giada, Da Ros, Lucia, Russo, Stefania, Bonotto, Marta, Belletti, Barbara, Baldassarre, Gustavo, Damante, Giuseppe, Puglisi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531252/
https://www.ncbi.nlm.nih.gov/pubmed/33072577
http://dx.doi.org/10.3389/fonc.2020.550185

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